Robert K Semple Selected Research

Epitopes

1/2018

Evaluation of anti-insulin receptor antibodies as potential novel therapies for human insulin receptoropathy using cell culture models.

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Robert K Semple Research Topics

Disease

39	Insulin Resistance 11/2023 - 11/2004
17	Lipodystrophy 10/2023 - 03/2006
11	Obesity 04/2024 - 11/2007
10	Fatty Liver 04/2024 - 02/2009
10	Type 2 Diabetes Mellitus (MODY) 11/2022 - 11/2004
8	Dyslipidemias (Dyslipidemia) 04/2024 - 11/2004
6	Neoplasms (Cancer) 01/2022 - 06/2012
5	Hyperinsulinism (Hyperinsulinemia) 11/2023 - 04/2010
5	Hypoglycemia (Reactive Hypoglycemia) 01/2021 - 05/2009
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2017 - 03/2006
3	Alstrom Syndrome 04/2024 - 07/2017
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 06/2011
3	Acanthosis Nigricans 03/2022 - 01/2007
3	Hyperandrogenism 01/2021 - 01/2007
3	Hyperglycemia 11/2020 - 11/2018
3	Hypertriglyceridemia 01/2017 - 02/2009
3	Dwarfism 10/2015 - 02/2008
3	Donohue Syndrome 01/2014 - 08/2007
3	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2010 - 03/2009
3	Congenital Generalized Lipodystrophy (Berardinelli-Seip Congenital Lipodystrophy) 01/2009 - 01/2007
2	Diabetes Mellitus 12/2023 - 12/2014
2	Metabolic Diseases (Metabolic Disease) 01/2023 - 03/2006
2	Weight Gain 01/2023 - 09/2010
2	Body Weight (Weight, Body) 01/2023 - 11/2007
2	Werner Syndrome (Werner's Syndrome) 09/2022 - 01/2020
2	Non-alcoholic Fatty Liver Disease 01/2022 - 08/2010
2	Vascular Malformations 11/2018 - 01/2018
2	Cardiomyopathies (Cardiomyopathy) 01/2018 - 07/2017
2	Coronary Artery Disease (Coronary Atherosclerosis) 12/2017 - 06/2011
2	Weight Loss (Weight Reduction) 10/2017 - 05/2015
2	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 01/2017 - 10/2013
2	Endometrial Neoplasms (Endometrial Cancer) 09/2015 - 08/2013
2	Genetic Risk Score 12/2014 - 10/2013
1	Autoimmune Diseases (Autoimmune Disease) 12/2023
1	Monoclonal Gammopathy of Undetermined Significance 12/2023
1	Paraproteinemias (Monoclonal Gammopathy) 12/2023
1	Congenital Hyperinsulinism 11/2023
1	Ketosis 11/2023
1	Epilepsy (Aura) 10/2023
1	Sturge-Weber Syndrome (Sturge-Kalischer-Weber Syndrome) 10/2023
1	Seizures (Absence Seizure) 10/2023
1	Optic Atrophy 01/2023
1	Gallstones (Gallstone) 01/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022
1	Tuberous Sclerosis (Bourneville's Disease) 01/2021
1	Hypopigmentation (Hypomelanosis) 01/2021
1	Psoriasis (Pustulosis Palmaris et Plantaris) 08/2020
1	Connective Tissue Diseases (Connective Tissue Disease) 08/2020

Drug/Important Bio-Agent (IBA)

46	Insulin (Novolin)FDA Link 04/2024 - 03/2007
21	Insulin ReceptorIBA 11/2023 - 06/2007
12	AdiponectinIBA 01/2023 - 06/2007
12	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 01/2007
10	Triglycerides (Triacylglycerol)IBA 10/2023 - 01/2009
10	Proteins (Proteins, Gene)FDA Link 01/2023 - 05/2008
7	HDL CholesterolIBA 01/2022 - 11/2004
6	B-insulinIBA 01/2023 - 06/2007
6	AntibodiesIBA 01/2021 - 06/2007
6	LipidsIBA 10/2020 - 03/2006
5	AutoantibodiesIBA 01/2023 - 05/2015
5	LeptinIBA 01/2023 - 01/2007
4	Fatty Acids (Saturated Fatty Acids)IBA 11/2023 - 01/2015
3	CalciumIBA 10/2023 - 01/2014
3	2,4-thiazolidinedione (thiazolidinedione)IBA 04/2023 - 11/2004
3	Phosphotransferases (Kinase)IBA 11/2017 - 10/2016
3	Neurokinin BIBA 01/2010 - 03/2009
2	metreleptinIBA 10/2023 - 04/2023
2	ThiazolidinedionesIBA 10/2023 - 04/2023
2	Vitamin D FDA LinkGeneric 10/2023 - 04/2008
2	AndrogensIBA 11/2022 - 01/2017
2	Apolipoproteins E (ApoE)IBA 01/2022 - 01/2013
2	C-PeptideIBA 01/2021 - 10/2018
2	Metformin (Glucophage)FDA LinkGeneric 08/2020 - 01/2020
2	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 01/2019 - 11/2017
2	Rosiglitazone (Avandia)FDA Link 01/2018 - 11/2004
2	Nonsense Codon (Nonsense Mutation)IBA 12/2017 - 08/2009
2	Nonesterified Fatty Acids (NEFA)IBA 01/2017 - 08/2010
2	Sex Hormone-Binding GlobulinIBA 12/2014 - 05/2008
2	DNA (Deoxyribonucleic Acid)IBA 06/2012 - 01/2009
2	Insulin-Like PeptidesIBA 01/2012 - 05/2010
2	pericentrinIBA 03/2011 - 02/2008
2	Insulin-Like Growth Factor I (IGF-1)IBA 05/2010 - 08/2007
1	ParaproteinsIBA 12/2023
1	Immunoglobulin G (IgG)IBA 12/2023
1	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 11/2023
1	MineralsIBA 10/2023
1	Anticonvulsants (Antiepileptic Drugs)IBA 10/2023
1	Hemoglobins (Hemoglobin)IBA 04/2023
1	Dynamins (Dynamin)IBA 01/2023
1	Serotonin (5 Hydroxytryptamine)IBA 01/2023
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022
1	SilverIBA 01/2022
1	HDL LipoproteinsIBA 01/2022
1	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2021
1	Testosterone (Sustanon)FDA Link 01/2021
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2020
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 08/2020
1	Methotrexate (Mexate)FDA LinkGeneric 08/2020

Therapy/Procedure

13	Therapeutics 12/2023 - 11/2004
2	Aftercare (After-Treatment) 12/2023 - 04/2023